Although you are very tired now and your family objects to your being together, I don't think you should break up with her. You have been together for six years, and both sides should know each other better and have deep feelings. If you break up for her debts and lose a hard-working girl, she is not lazy and loses money playing cards and gambling. It is normal to lose money in stock trading. There are too many people who lose money in stock trading.150,000 is not a lot, as long as you two Qi Xin work together.
You can't measure your feelings with money. Find someone who is in tune with feelings and life will be much happier.