Interlocking protection system includes input equipment, logic structure and output system. The input system can be cam, hinge and bolt of mechanical interlocking part, the logic system includes AC contactor and intermediate relay, and the output equipment includes circuit breaker. The process of protection is to obtain the state (on and off) of the protection device through actuators such as cams, and then make logical judgments through electrical signals/optical signals/electromagnetic signals, and finally output them as control signals to control the start or stop state of the equipment. If the protective door is opened and the contact switch of the output system is closed during the normal operation of the equipment, the logic judges that the protective door is opened and the equipment will be automatically powered off. In both cases, it is to prevent the risk of personnel exposure when the equipment is running. Of course, there are many other details of the interlock protection system, including the interlock protection system, the requirements of forced disconnection structure, the selection of interlock devices, the safety design of the interlock protection system, and the reduction of artificial shielding.