First of all, there are actually many tumor-related pathways. Generally speaking, tumor-related pathways include cell signal transduction (akt, notch, MAPK, etc. ), cell damage repair (ATM, NHEJ, etc. ), cell cycle regulation (Cdk), gene expression regulation (such as p53) and cell migration, which generally overlap. Although most pathways are more or less involved in the occurrence of tumors, what is directly related is generally what I mentioned, which mainly acts on the occurrence, maturation and migration of tumors.
Secondly, through the process that this tumor gene may participate in, I think it may participate in the occurrence of tumor, including: the regulation of cell morphogenesis (because the cell morphology will change during the formation of tumor cells); Regulation of gene expression (for example, p53 can inhibit the expression of cancer-related genes, but this effect is too broad, so it can be said that all cell activities are related to gene expression. Is your gene a transcription factor? If so, this is probably why it is directly involved in the development of cancer); Positive regulation of protein activity (as in the previous point, this broad-spectrum process can participate in any aspect); Response to corticosteroids (possibly regulating cell signals); By reacting to some corticosteroids); Positive regulation of macromolecular biosynthesis process (regulation of macromolecular biosynthesis may also affect protein expression); The formation of anatomical structures involved in morphogenesis (also explained in morphogenesis).
Finally, this method will not greatly narrow the scope, but if you combine the functional research of your target protein (if there are relevant literature reports or you know that the target protein has enzymatic activity) or location analysis, you can greatly narrow the scope.
I hope I can help you. If you have any questions, we can continue our discussion.