The best method of grain depot liquidation needs to be combined with the actual situation. Grain depot liquidation needs different ways, such as selling to grain enterprises or feed enterprises, transferring to futures companies or commodity trading platforms. When choosing the liquidation method, we should comprehensively consider the market situation, inventory, grain varieties, quality and other factors to ensure the best liquidation effect. We should also pay attention to policies and regulations, logistics costs and other factors, formulate a scientific liquidation plan and reduce the risk of loss.