1. Many commonly used Chinese medicines recorded in China Pharmacopoeia come from two, three, four, five or even six species of the same genus. More than five kinds of Chinese medicines are as follows.
A. hippocampus
B. Fritillaria cirrhosa
C. Bupleurum
D. Gentiana macrophylla
E. concha Haliotidis
2. The following statement about the metabolic kinetics of tetrandrine is correct.
A. drugs enter the liver through the portal vein.
B, the metabolites of drugs are bound alkaloids.
C the drug has typical characteristics of enterohepatic circulation.
D. under different doses, the C-T curve presents a typical single peak phenomenon.
E. under different doses, the C-T curve presents a typical bimodal phenomenon.
3. Microscopic identification of licorice powder is characterized by
A. fiber bundle
B. calcium oxalate square crystal
C. Cork cells are reddish brown.
D. the catheter is very large
E. calcium oxalate cluster crystal
4. The following statement about traditional Chinese medicine injection is correct.
A. A traditional Chinese medicine injection made of various components, wherein the content of components with definite structure is not less than 60% of the total solid content.
B decoction pieces of traditional Chinese medicine injections shall be extracted, purified and made into semi-finished products according to the prescribed methods, and the semi-finished products shall be used for feeding.
C. Traditional Chinese medicine injection made of active ingredients, with a purity of over 90%.
D. When injecting injections, the additional amount should be increased according to regulations.
E. The contents of protein, tannin and resin should be checked for traditional Chinese medicine injections.
Answer analysis
1. Analysis: This topic mainly investigates the influence of varieties on the quality of medicinal materials. Many commonly used Chinese medicines recorded in China Pharmacopoeia come from two or more genera, such as Bupleurum (2), rhubarb (3), licorice (3), Gentiana macrophylla (4), hippocampus (5), Fritillaria cirrhosa (6) and concha Haliotidis (6).
2. The answer is ABCE. Analysis: This topic focuses on the pharmacokinetics of tetrandrine. The C-T curve of tetrandrine at different doses presents a typical bimodal phenomenon. Drugs enter the liver through the portal vein and are absorbed by the liver in large quantities. It is metabolized into bound alkaloids and excreted into the intestine through bile. After being hydrolyzed by intestinal flora, the combined alkaloids release the prototype drug tetrandrine, which is absorbed again, resulting in a bimodal phenomenon. It has typical characteristics of enterohepatic circulation.
3. answer ABCD. Analysis: This topic mainly investigates the microscopic identification of roots and rhizomes of traditional Chinese medicine. Microscopically, licorice powder was identified as a fiber bundle with a diameter of 8 ~ 14? M, the wall thickness is slightly lignified, and the surrounding parenchyma cells contain calcium oxalate square crystals to form crystal fibers. Calcium oxalate crystals are more common. Cork cells are reddish brown, polygonal and slightly lignified. Containers with edge holes are larger.
4. answer BCDE. Analysis: This topic mainly investigates the preparation and quality requirements of traditional Chinese medicine injections. Traditional Chinese medicine injection made of active ingredients, the purity of active ingredients should reach more than 90%; On the basis of determining the total solid content, the content of components with clear structure should not be less than 80% of the total solid content. The decoction pieces of traditional Chinese medicine injection should be extracted and purified according to the methods specified under each variety to make semi-finished products, and the semi-finished products should be fed to make finished products; When injecting injections, the additional amount should be increased according to the regulations; The related substances of traditional Chinese medicine injection refer to the substances that may be contained in the injection after the extraction and purification of traditional Chinese medicine. Generally protein, tannin, resin, etc. It should be checked, and oxalate and potassium ions should also be checked for intravenous injection.