What are the doubts about bone metastasis of lung cancer?
1, the cause of bone metastasis
Cancer cells transfer to bone with blood circulation, which is called bone metastasis. Although bone tissue is hard, it still belongs to tissues and organs, and it cannot be separated from blood to provide nutrition. As long as there are cancer cells in the circulatory system, even hard bone tissue will metastasize.
2. Other cancers have no bone metastasis.
In addition to lung cancer, there are many cancers prone to bone metastasis, such as gastric cancer, prostate cancer, breast cancer and thyroid cancer. If cancer patients have unexplained bone pain and dyskinesia, they need to see a doctor immediately to see if there is bone metastasis.
3. Which bones are the high-risk sites of lung cancer metastasis?
Bone metastasis of lung cancer mainly occurs in the spine and proximal trunk. The spine includes many kinds, such as lumbar vertebrae, cervical vertebrae, spine and sacrum. In the middle of the dorsal torso. In addition, the sternum, ribs and femur are also prone to bone metastasis.
4. Significance of early diagnosis and treatment of bone metastatic carcinoma.
Under normal circumstances, there are osteoclasts and osteoblasts in bones, the former are destructive cells and the latter are generative cells. Usually, bone tissue is in a state of dynamic balance, and it is undergoing destruction and reconstruction every day. However, after bone metastasis of lung cancer, osteoclasts can be activated and cells are constantly destroyed, thus breaking its balance and reducing bone stability, which in turn leads to a series of symptoms. Once patients with lung cancer have spinal cord compression and pathological fracture, their survival time will be shortened, so early identification and treatment are very important.
5. Symptoms of bone metastasis
Bone pain is one of the typical symptoms of bone metastasis, followed by pathological fracture. Some people will also have symptoms of spinal cord compression, such as lower limb discomfort, lumbar disc herniation, defecation dysfunction and so on. When doing blood biochemical examination, blood calcium can be found to be elevated.
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Lung cancer patients suspected of bone metastasis need to go to the hospital immediately for relevant examinations, such as radionuclide bone scanning, ct, magnetic resonance imaging and X-ray scanning. They can also take blood tests to see the levels of alkaline phosphatase and blood calcium. Generally, bone metastasis occurs in the late stage of lung cancer, and the ultimate goal of treatment is to improve the quality of life and prolong the survival period. Comprehensive treatment can be carried out through targeted therapy, radiotherapy and chemotherapy, immunotherapy, etc., and psychological adjustment is also needed.
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