In the 215 New York Marathon, eight special runners were particularly eye-catching, namely Jimmy Choi and seven other Parkinson's patients. Since he was diagnosed with Parkinson's disease in 23, Jimmy Cui has been exercising all the time. He has never given up, and he has gradually recovered his body function because of continuous blood exercise, thus having the feeling of going back in time. According to the Runner's World website, 41-year-old Jimmy Cui suffers from Parkinson's disease. The main pathological change of this disease is the rapid degeneration of basal ganglia and substantia nigra brain cells at the bottom of the brain, which is related to the inability to produce enough neurotransmitter Dopamine and the enhancement of choline. Dopamine is needed in the brain to direct muscle activity; Lack of enough dopamine can lead to various activity disorders. Therefore, when Jimmy's brain tells his body to move, his muscles may not be able to receive this message. Sometimes, his muscles even twitch and tremble. Jimmy Choi, a Chinese patient with Parkinson's disease, loves horse racing, which is after he finished the Chicago horse race in 214. ? THE MICHAEL J. FOX FOUNDATION weighs a thousand pounds when running

When running, he feels that his right foot weighs five pounds. His shoulders and neck were cramped, his mouth was watering, and his right arm could barely swing. Sometimes, his toes curl up unconsciously, and he can only relieve them by walking. "It seems that I have to use the ground to make * * * for my toes. Jimmy said, but even if he is very tenacious, his body will always be out of control. But that didn't stop Jimmy from running. By the end of 215, he had accumulated about 2, miles. Jimmy lives in the suburbs of Chicago. On weekdays, he will run on nearby roads and trails. From 212 to the end of 216, Jimmy has completed 7 half-horse races and 11 full-horse races, including the Chicago Marathon in early October 215, when he finished in 4 hours, 5 minutes and 21 seconds. In 215-16, he participated in the new york Horse for two consecutive years, and in 216, this was his 11th all-horse race. His best result in new york Horse was 3 hours and 56 minutes. Through continuous participation in the competition, Jimmy has raised nearly $1, for Team Fox of Michael J. Fox Foundation, a foundation that focuses on Parkinson's disease research. Team Fox is a team that focuses on raising public awareness of Parkinson's disease through sports. Jimmy believes that running helps to control the symptoms of Parkinson's disease and delay its development. When interviewed in 215, he said, "In the past three years, I feel that there is a feeling of going back in time. Through the Fox team, he contacted some other patients with Parkinson's disease, and seven of them also signed up for the new york Horse. "We help each other and support each other, just like family members, which also helps my treatment. Jimmy Choi finished the 215 new york Horse. ? Tcsnycmarathon joins Michael Fox Foundation to run to delay the symptoms of Parkinson's disease

Jimmy is a sports enthusiast. In high school, he participated in wrestling, basketball and football. After graduating from college, he worked in an internet company. At first, his fingers always twitched strangely, and he thought it was caused by work pressure and didn't care. In 23, when Jimmy was 27 years old, doctors diagnosed him with early-onset Parkinson's disease. For eight years, he had to take drugs containing two components, carbidopa and levodopa. The combination of these two components can supplement the dopamine that his brain lacks. But he didn't want to face the illness, so he just took the medicine instead of seeing a doctor. With the continuous development of his illness, his self-care ability is also declining. At the age of 36, he was 18 cm tall and weighed 113 kg, so he could only walk with crutches. When one day he came downstairs with his baby son Mason in his arms, the lowest point of his life came at this moment, and he couldn't control his body, so both of them rolled down the stairs. He thought, "This is crazy. I'm still young. I don't want to be a burden to my family. He refused to bow to the disease and began to seek what he called "magic therapy". He signed up for a clinical experiment of stem cell medicine. Although he was not sure whether he was effectively treated or psychologically, the experiment helped him. He was able to walk without crutches and then he was able to run slowly. On a flight, he read a Runner's World magazine provided on board, in which he read a story about a Parkinson's patient who participated in a sports competition and won the second place. That story inspired Jimmy. He thought to himself, "If he can do it, why can't I?"? So he began to run a long distance, and the distance was extended to several miles. His first road race was Parkinson's 5K, and then he took part in a semi-horse race in Cottage Grove, Wisconsin in April 212, and then he couldn't stop. "The more I run, the better I feel," he said. Studies have shown that riding a bicycle, running on a treadmill, Tai Chi Qigong and other sports can help alleviate the symptoms of Parkinson's disease. Scientists speculate that physical activity can increase the amount of dopamine in the brain or form a new communication channel between brain and muscle to replace the destruction of the original communication mechanism between brain and muscle by this disease. Jimmy believes that this love of running mentality-focusing on swinging his arms and stepping forward-can help him regain his physical function. "This is a muscle memory or just a habit," he said. "Now when I walk, I can walk much more stably. I can be more balanced and stable when I go up and down the stairs. In September 212, Jimmy participated in the Chicago Half Marathon, and then he set his sights on an all-horse race in October. However, at that time, the whole horse of this marathon was already fully registered, so he had to seek ways to raise funds for public welfare to give himself a chance to run. At this time, he discovered the organization TEAM FOX, and quickly joined it and became an active member. Stephanie Paddock, the foundation's employee in charge of TEAM FOX, clearly recalled meeting Jimmy for the first time in the Chicago Marathon: Jimmy shaved a foundation fox LOGO on his head, and later he would have the same hairstyle every year in this competition, but later he added the Chicago flag and skyline behind the fox. Jimmy also set up a community on Facebook for TEAM FOX members who are also Parkinson's disease. They exchanged running skills and shared their own challenges, and organized a team to challenge a 5-mile relay race held in spring. "Every once in a while, I will see some messages on it that I fell down from running or had difficulty running or swinging my arms during road running," Stephanie said. "However, I often see a whole series of cheering responses immediately, and it feels really sweet. Jimmy Choi and Team Fox players. ? The future goal of THE MICHAEL J. FOX FOUNDATION is to challenge the IRONMAN Super Ironman

Now Jimmy runs a total mileage of about 5 miles every week. He usually chooses to wait until the children are asleep at night before going out for a run. One symptom of Parkinson's disease is insomnia, so running at night is the most relaxed and comfortable for him. On average, he takes the above medicine once an hour every time he exercises, but sometimes he needs to take more to make his muscles more energetic. Therefore, the route he runs always revolves around the pharmacy or the homes of his two brothers or parents, who all live in communities not far away. When asked about the goal of participating in the 216 new york Horse Race by the organizer of new york Horse Race, Jimmy said that he set himself to finish the race in 3 hours and 2 minutes, but he was not sure that he could finish it with his still limping right leg. However, he is a little excited about his long-distance goal, because he wants to challenge the IRONMAN Super Iron Man. "Swimming is the most challenging thing for me," he said, because he will definitely stay in the water for more than an hour if he takes part in the competition. "It's not because I can't swim that far, but how can I take medicine in the water? However, these may not be a problem in the future, because there have been some experimental studies, such as a waterproof irrigation device that can continuously supply liquid medicine, or a treatment that can completely exempt him from drug dependence. These possibilities have also become one of the driving forces for Jimmy's continuous fundraising. Although his wife, Chelsea, doesn't run, she has always been his best cheerleader. They also organized the first road race "Shake it Off 5K" this spring. The name comes from Taylor's song of the same name, from Jimmy's muscle twitching that he wants to get rid of Parkinson's disease, and from his motivation to get back on his feet from all kinds of challenges in his life. He wants to encourage everyone to get rid of the control of the disease and live a happier life. In September 215, his 8-year-old daughter, karina, also completed her first triathlon for TEAM FOX and raised $2,5 for the organization. "When the game was over, the first thing she said to me was, where can I sign up for the next game? "Jimmy said with a smile," She loves sports as much as her father, which really makes me very happy. My daughter's success also inspired me. Jimmy said that although the New York Marathon was a very difficult race, he would still bravely run forward. Jimmy Choi took part in road races everywhere to raise money for the Michael Fox Foundation. ? THE MICHAEL J. FOX FOUNDATION