The venom in the cartoon was taken by the Life Foundation. They took Eddie and removed the venom with some technology. Then the venom was stimulated by scientific means, so that he split into five daughters and merged with five mercenaries of the Life Foundation, leading to riots, howling, extreme pain, swallowing and flogging.

In the movie "Venom", the riot came to the earth with venom, but he took advantage of the opportunity of the spaceship crash to escape, and finally parasitized on the foundation boss Drake, ready to launch a rocket to bring other creatures to the earth. After a fierce battle, the riot was defeated by venom.

The strength and speed of howling are excellent, and she will appear in Venom 2. Howling in the trailer can turn hands into spears and hair into spikes to attack the enemy. Moreover, the film will probably retain her relationship with the Holocaust.

The host of the serum is also Eddie Brock. In the cartoon, Eddie once got rid of the venom. Later, due to the power of Mr. Negative, Eddie's own antibody became serum. Serum is the natural enemy of venom and can cure people who are parasitized by venom.