Date of birth:1April 964
Professional and technical position: professor
Major: biochemistry and molecular biology
Tutor level: doctoral tutor
Tutor category: academic type
Final education: 1993, graduated from China Academy of Medical Sciences, Institute of Basic Medicine of Peking Union Medical College, Ph.D. in Cell Biology.
SETTING: Institute of Genetic Engineering, Southern Medical University
Ma Liwen, Director of Institute of Genetic Engineering, Guangzhou Southern Medical University. The concepts of "sub-health" and "subclinical" were put forward for the first time in China, but the concept of "subclinical" is not well known. The first scientist in China to carry out research on applied gene chips, the top ten' No.1' outstanding women figures in Guangdong, and the first top ten independent innovation women figures in Guangdong. The invention of the technology of isolating and displaying genes and discovering new functions of genes-restricted display technology has great scientific significance and application prospect for the research of post genome project, gene index, gene expression regulation and gene chip. It is the first in China to set up a gene chip laboratory, carry out research on gene chip innovation, and make independent innovation on three key technologies that limit the rapid development and application of gene chip technology, and make original breakthroughs. * * * applied for 8 patents, including 5 invention patents and 2 utility model patents, and established a biochip high-tech platform with independent intellectual property rights. The successful development of gene expression profile chip of human erythroleukemia K562 cells laid a foundation for screening effective anticancer targeted gene therapy drugs. The first finisher won the China Youth Science and Technology Award, the first prize of Guangdong Science and Technology, and the first prize of China People's Liberation Army Science and Technology Progress Award. 1995 won the China Youth Science and Technology Award; 1998 was named "Science and Technology Rising Star" by the General Logistics Department; 1999 was rated as "outstanding returned overseas students of the whole army"; In 2000, he was awarded the first batch of outstanding backbone teachers by the Ministry of Education. 200 1 was awarded the title of "March 8th Red Flag Bearer" and "Ninth Five-Year Plan" Science and Technology Star in Guangdong Province. In 2002, he was awarded the title of "Outstanding Young Entrepreneurs Returned from Studying Abroad" in Guangzhou. Main research directions:
1. Gene diagnosis (including gene chip) and gene therapy
2. Bioinformatics
Academic posts: Director of Institute of Genetic Engineering, Southern Medical University, Director of South China Biochip Research Center, Director of Guangdong Biochip Key Laboratory, Director of Shanghai University Electronic Research Center; Director of China Bioengineering Society, Vice Chairman of Guangdong Society of Biochemistry and Molecular Biology; Member of academic degree evaluation committee, Guangdong Province; Member of the evaluation expert database of the life science department of the National Natural Science Foundation of China. Member of the jury of China Medical Science and Technology Award and China Medical Youth Award; Standing Editorial Board of Medical Molecular Biology (Foreign Medical Molecular Biology Volume) 1, Ma,. Methods and applications of DNA chip technology. Guangdong Science and Technology Press, 2002.
2. Horse, Zheng Wenling, man. Experimental handbook of HIV molecular diagnosis. People's Health Publishing House, 200 1.
3. Ma, from Zheng Wenling. Molecular oncology. Science Press, major awards in 2003:
1, "Development of K562 cell gene expression profile chip and its application in the regulation of malignant expression of human erythroleukemia cells" won the first prize of Guangdong Science and Technology in 2003 (the first completed person).
2. The "Development and Application of Rapid Detection Chip for Major Infectious Diseases" won the first prize of military scientific and technological progress in 2003.
3. "Establishment of gene chip technology platform and its application in expression profile research and pathogen detection" won the third prize of China Medical Science and Technology in 2006 (the first person to complete it).
Research topic:
1, detection of EV7 1 virus by gene chip /RT-PCR, saving 2 1 1 Phase III construction (2008 5438+0-201.12), 2008.
2. Study on the molecular action pathway of PIN1gene in the occurrence of liver cancer, supported by the Doctoral Foundation of the Ministry of Education (20 10.3-20 12.3), 60,000 yuan.
3. Genetic study of longevity population in Sanshui District of Guangdong Province, Sanshui Science and Technology Plan (2008. 10-20 10),150,000 yuan.
Research on EGS-RNAi technology platform for developing new anti-AIDS drugs with special effects. Guangzhou Key Science and Technology Project (2007-20 10),10 million yuan.