Meimei waited for a long time to get pregnant, and paid special attention to the baby in her belly. She didn't dare to be careless about any pregnancy test. A few days ago, she had a folic acid metabolism gene test. Today, she got the report. What does it show? Folic acid test 677tt homozygous mutation? Meimei suddenly the sky fell and cried and asked the doctor what to do. The doctor told Meimei the precautions and let Meimei go home and have a pregnancy test on time. In fact, most people are right? Folic acid test 677tt homozygous mutation? It's not clear what it means. What's the effect of folic acid test on homozygous mutation of 677tt? Let's take a look at the comparison table of folic acid gene test cc, ct and tt.

folic acid gene test is the detection of folic acid metabolism gene, which is to check the human mthfr gene and mtrr gene by means of genetic technology to understand the folic acid utilization ability of the tested people, that is, to understand the specific situation and existing risks of folic acid absorption and metabolism of different individuals, and then doctors can recommend more accurate folic acid supplement dosage to the tested people according to this. Cc, ct and tt in folic acid gene detection actually refer to three gene types of mthfr gene. If cc is positive, it shows that folic acid utilization ability is very good; Ct is positive, indicating that folic acid utilization ability is average, but it is still within the normal range; If tt is positive, it means that folic acid utilization ability is very poor, pregnant women need to double folic acid supplementation, and may also need to supplement folic acid throughout pregnancy.

In addition, the gene mutation at the 677tt locus will lead to the decrease of mthfr enzyme activity, which will lead to the accumulation of homocysteine in the body and cause hyperhomocysteinemia, which is an important risk factor for cardiovascular and cerebrovascular diseases and birth defects. Simply put, folic acid is an obstacle to digestion, absorption and excretion, which will have the following effects: pregnant women will induce their own abortion, pregnancy-induced hypertension and so on. Fetal words will have congenital defects (cleft lip, spina bifida, low birth weight) and so on. However, pregnant women don't have to be too nervous. If the homozygous mutation of 677tt is detected, they should take folic acid regularly under the guidance of a doctor, continue to complete various prenatal tasks on time, and pay attention to the habits of life and diet. However, they should also closely observe the fetal development and placental amniotic fluid, and seek medical advice in time if they feel unwell.

After the folic acid gene test, if the test results are normal, it is suggested that pregnant women should pay more attention to rest, have regular pregnancy tests and do a good job in pregnancy tests. However, if the test results are abnormal, folic acid should be properly supplemented for treatment under the guidance of a doctor.