This kind of premature senility (premature senility in children) is a genetic disease. The aging process of the body is 5 to 1 times faster than normal. The patient looks like an old man, and the organs also decline quickly, resulting in the decline of physiological function. Symptoms include thin figure, hair loss and late teething. Sick children can only live to 7 to 2 years old, and most of them will die of aging diseases, such as cardiovascular disease.

At present, there is no effective treatment, and only drugs are used to treat it.

This disease was first reported by Hutchinson in 1886. Although progeria is a congenital genetic disease, it is still uncertain whether it is autosomal recessive or dominant. This disease is a syndrome, characterized by delayed development, and progressive senile degenerative changes occur in infancy. The aging process of the patient's body is very fast. Children with this disease are rarely over 13 years old, and about one in every eight million newborns suffers from this disease.

Symptoms

As a newborn, the patient is usually normal at birth. However, within a year, their growth rate slowed down, and soon, they were shorter and lighter than other normal children. Although he has normal intelligence, his hair is bald, his skin is wrinkled and flabby, his teeth fall off, his nose is flat and contracted, his face and chin are too small to match the size of his head, his eyes are sunken, and there are looming senile plaques on his cheeks and arms. He looks like an 8-year-old man.

They also suffer from a variety of geriatric diseases, such as joint stiffness, hip dislocation and serious cardiovascular diseases. However, other diseases related to normal elderly people, such as cataracts and osteoarthritis, do not appear in children with premature senility.

Etiology of the disease

On June 17th, 24, researchers of the Premature Aging Research Foundation announced that the mutation of Lamin A gene was the cause of the gradual degradation of cell structure and function in children with Premature Aging. LMNA is mainly responsible for the interconnection between nuclei. Once it mutates, it will make the nuclei in an unstable state, accelerate the development and aging of the human body, and its speed is equivalent to 8 times the normal speed, thus leading to premature aging.

no effective treatment has been found

none of the treatments for premature senility have been proved to be effective at present. Most treatments focus on reducing complications, such as coronary artery bypass surgery or low-dose aspirin. Patients may also benefit from high-calorie diet therapy. In addition, according to the Daily Science website, a new study pointed out that vitamin C in the small medicine box at home may be able to treat disorders that can accelerate aging, especially premature aging in adults.