Off-pump beating coronary artery bypass grafting, mini-incision minimally invasive coronary artery bypass grafting, coronary heart disease hybridization, robot-assisted heart surgery and stem cell transplantation are the first in China to treat heart failure after coronary heart disease myocardial infarction. He presided over and participated in the national "863" scientific and technological key projects, the "Tenth Five-Year Plan" national scientific and technological key projects, the National Natural Science Foundation, the major scientific research projects of Shanghai Science and Technology Commission, and multi-center clinical research at home and abroad. The research on stem cell transplantation to improve cardiac insufficiency after myocardial infarction, the clinical application of minimally invasive coronary artery bypass grafting, and the treatment of end-stage heart disease by orthotopic heart transplantation have won awards such as China Medical Award, Shanghai Science and Technology Progress Award, Shanghai Medical Science and Technology Award, Shanghai Clinical Medical Achievement Award and Shanghai Talent Development Fund. There are more than 1 10 papers published at home and abroad, including 3 SCI papers10. Participated in the compilation of 9 monographs on cardiothoracic surgery. 36 graduate students have been trained.