1. National Natural Science Foundation of China: Structure-activity relationship of anti-rheumatic arthritis molecules based on sinomenine (20872060,09-11). 2.973 Plan: Basic research on the application of microfluidic technology in chemistry and biomedicine (participation, 2007cb714504,07-1). 3. Natural Science Foundation of Jiangsu Province: Design and Optimization of STAT3 Selective Inhibitor and its (BK2009240- 1 1). 4. Major research plan of the National Natural Science Foundation: A new regulatory mechanism of life-death transition of activated T cells based on astilbin and its analogues (participation, 909 13023, 20 10- 13).