Most of bilirubin in the body comes from hemoglobin released by aging red blood cells, including indirect bilirubin and direct bilirubin. Indirect bilirubin is transported to the liver through blood, and direct bilirubin is produced through the action of liver cells. Elevated bilirubin is seen in:
(1) Liver diseases: acute icteric hepatitis, acute yellow liver necrosis, chronic active hepatitis, liver cirrhosis, etc.
(2) Extrahepatic diseases: hemolytic jaundice, transfusion reaction due to blood group incompatibility, cholecystitis, gallstones, etc.
According to the test results you provided, the total bilirubin and direct bilirubin are on the high side. There is something wrong with the gallbladder, but it is not seriously high, and the normalization of other indicators is not a big problem. You can refer to TCM conditioning treatment. The gallbladder wall is rough but has no obvious thickening, indicating mild gallbladder inflammation, but it is not very serious. The landlord can rest assured, pay more attention to diet, eat less spicy and greasy, and eat more light. In terms of traditional Chinese medicine, he can take some drugs to soothe the liver and benefit the gallbladder, such as Jigucao capsules or Shugan Lidan tablets!
Supplement: "B-ultrasound found that gallbladder mucosa is slightly rough, whether it is a disease. It depends on whether you have discomfort or dull pain in the gallbladder area of the right upper abdomen, which affects your diet. If there is no such discomfort, that is, the gallbladder mucosa is rough, it can only be used as a reference for regular follow-up observation. Treat inaction as a disease. If the clinical symptoms are aggravated, then gallbladder mucosa roughness can be called a disease. You have to go to the hospital for further examination.
What is the reason of high total bilirubin?
The life span of human red blood cells is generally 120 days. After red blood cells die, they become indirect bilirubin (I-Bil), which is converted into direct bilirubin (D-Bil) through the liver, forming bile, which is discharged into the biliary tract and finally discharged through feces. The sum of indirect bilirubin and direct bilirubin is total bilirubin (T-Bil). Obstacles in any of the above links will cause jaundice. If too many red blood cells are destroyed, too much indirect bilirubin is produced, and the liver can not be completely converted into direct bilirubin, which can lead to hemolytic jaundice; Hepatocellular jaundice occurs when liver cells are diseased, or because bilirubin cannot be converted into bile normally, or because liver cells are swollen, bile ducts in the liver are compressed, bile excretion is blocked, and bilirubin in the blood is increased. Once tumors or stones occur in the extrahepatic biliary system, the biliary tract will be blocked, bile can not be excreted smoothly, and obstructive jaundice will occur. Jaundice in patients with hepatitis is generally hepatocellular jaundice, that is, both direct bilirubin and indirect bilirubin are increased, while in patients with cholestatic hepatitis, the direct bilirubin is mainly increased.
The normal value of total bilirubin is1.71-17.1μ mol/l (1-10mg/l), and the normal value of direct bilirubin is1.7/kloc.