It is not clear whether tenofovir disoproxil fumarate will be secreted into milk. However, the results of animal studies show that there is insufficient information about the effects of tenofovir disoproxil fumarate on newborns or infants, and the risks to lactating children cannot be ruled out. Therefore, tenofovir disoproxil fumarate fumarate tablets should not be used during lactation.
Breastfeeding is a special physiological period for women, including the puerperium within 42 days after delivery. The puerperal maternal system changes greatly, because there is a big wound in the postpartum uterus, during which diseases such as infection are prone to occur. When breast-feeding women have a cold or bacterial infection, they often take some drugs. When mommy is breastfeeding her baby, drugs can enter the baby through breast milk, but the contents of different drugs in the milk are quite different. An important principle of medication during lactation is that it can not only effectively treat the mother's disease, but also minimize the impact of medication on the baby.
1 19 10/9, Gilead Technology announced that China National Pharmaceutical Products Administration had approved the marketing of once-a-day propofol fumarate tablets (Velide, TAF, 25mg based on propofol tenofovir) for the treatment of chronic hepatitis B in adults and adolescents (19). It is reported that Willard is considered to be the best hepatitis B drug at present.
Veride is a new target prodrug of tenofovir. Studies have shown that its antiviral effect is similar to that of tenofovir disoproxil fumarate fumarate /TDF (300mg), but its dosage is only one tenth of that of the latter. The data showed that compared with Veride, Veride has greater plasma stability and can deliver tenofovir to hepatocytes more effectively, so it can be administered in a smaller dose, thus reducing the content of tenofovir in circulation. Clinical experiments show that Veride can improve the safety parameters of renal bone laboratory compared with Veride.
The above is an introduction about whether Velide can be used during lactation. Breast-feeding mothers must use drugs with caution. It is wise to explain to the doctor that you are breastfeeding when you need medication. Try to use drugs that can't pass through breast milk, and don't use drugs at will.