Big O stands for the vast sky. The blue sky is synonymous with "openness" and "freedom", at the same time, the sky also symbolizes "intellectuality" and "future". Otsuka Group uses the gradual blue sky to set off the profound and broad corporate connotation, while the red "little O" represents Otsuka Pharmaceutical Company's ever-jumping childlike innocence in developing products and the source of creativity and vitality that will never dry up.

The combination of two graphics with different sizes up and down maintains a clever sense of balance, and the combination of soft and friendly Otsuka characters reflects "a beautiful space full of health and happiness for human beings", and Otsuka Pharmaceutical continues to contribute to human health and a better life.