Liushen Pill, black oil, as thin as mustard seed, is a good medicine for treating throat diseases and boils. Now it is a famous characteristic variety of Shanghai Leiyunshang Pharmaceutical Co., Ltd., and Liushen Pill has been published for more than a hundred years. When the Lei family applied for opening in Shanghai, Lei Zifan, a descendant of Qi Sanfang, opened a small pharmacy named "Lei Tongjun Tang" in Fangbang Road, Xiaodongmen, and only hired two employees to handle a small amount of self-produced Chinese medicine. At this time, Lei Zifan had a secret recipe of Liushen Pill, which was obtained by his father Lei Zichun and passed on to him. In Suzhou Tonghefang's hometown, it was handmade by his wife and daughter and brought to Shanghai for sale. Named "Lei Zifan brand Liushen Pill". Rezifan's handwritten small paper advertisements posted on walls and telephone poles attracted many customers, including Japanese, thus opening up sales and providing a small number of exports. In the 28th year of Guangxu reign in Qing Dynasty (1902), the grandchildren of the Lei family collectively invested 10,000 yuan in Dayang to buy out the right to produce and operate Liushen Pills at one time. After the buyout of the patent right, the trademark of "Leizifan Liushen Pill" was cancelled immediately, the original supply channels were all suspended, and "Leitong Juntang" closed down. Since then, Liushen Pill has become a patented product of Lei. After technical transformation, the output increased and the market expanded, it became a famous and special product sold well at home and abroad in Leiyunshang drugstore. Liushen Pill has an immediate effect on various throat diseases and furuncle. Therefore, people call Liushen Pill "life-saving medicine". The fame of Liushen Pill has attracted many drug dealers' imitation, but the curative effect is not good because the alchemy process is not as good as Lei's. After liberation, the government protected the manufacturing technology of "Shile Liushen Pill" as a state secret. "Shile Liushen Pill" is now a national first-class protected variety of traditional Chinese medicine, and has won the national quality gold medal for three times, as well as the title of Shanghai quality product and Shanghai famous brand product. In May 2003, "Shile Liushen Pill" was awarded the title of well-known trademark in China. "Shile Liushen Pill" has pure raw materials, which can be taken orally or used externally. It has good antibacterial and anti-inflammatory effects, as well as sedative, anticonvulsant and cardiotonic effects. It is suitable for acute and chronic tonsillitis, stomatitis, periodontitis, parotitis and acute and chronic pharyngolaryngitis caused by heat accumulation and toxic fire. It can also be used for unknown swelling, infantile febrile convulsion and various internal diseases. It is famous for its centuries-old secret recipe and magical curative effect. {Family medication} "Shile Liushen Pill" has the functions of cooling and detoxifying, diminishing inflammation and relieving pain. It is suitable for sore throat, sore throat, throat wind, throat carbuncle, single and double moth, children's heat carbuncle, carbuncle, furuncle, breast carbuncle, hair back, nameless swelling poison, etc.