Augmentin extended-release tablets are white oval-shaped. (National Library of Medicine) "KDSPs" Auffin is the brand name for a class of antibiotics known as amoxicillin in combination, which are used to treat a wide range of illnesses, from bronchitis to Lyme disease. It is one of the most commonly used antibiotics in children and is often used for ear infections. Beneficial

Antibiotics work by attacking the cell walls of bacteria that harm the body or by preventing bacteria from replicating. [How do antibiotics work? The drug "KDSPE" "KDSPs" is a combination of two active ingredients: amoxicillin and clavulanic acid. Together, these drugs fight bacteria that are usually resistant to amoxicillin. "KDSPE" and "KDSPs" antibiotics can also be used in animals. Ruminants, pigs, horses, dogs, cats, and poultry are often prescribed enhancers to treat a variety of ailments.

Enhancers used are usually taken orally, as pills for adults, or as liquid (usually flavored) suspensions for children. Dr. Alasdair Geddes, emeritus professor of infectious diseases at the University of Birmingham in the United Kingdom, said doctors often prescribe this drug because it can fight a variety of disease-causing bacteria. "When I travel, I always have some booster in my bag" because it fights many common infections, according to some clinical trials of OkMin. KDSPE "KDSPs" Auffin is available in pediatricians' offices and is effective when prescribed for ear infections. It is resistant to amoxicillin, sore throats, and certain eye infections. This drug is also an effective treatment against bacterial causes of bronchitis and tonsillitis (although many strep throats are caused by viruses).

Additionally, the drug can fight pneumonia, urinary tract infections, gonorrhea, and skin infections. The drug is also considered a good candidate to treat Lyme disease, chlamydia, sinusitis, gastritis and peptic ulcers, according to a 2011 study in the International Journal of Pharmacy and Pharmaceutical Sciences. Some studies suggest that while protein boosting has not been conclusively proven to be safe during pregnancy, it is unlikely to cause harm to pregnant women or the fetus, according to a 2004 study in the British Journal of Clinical Pharmacology. harm. The Mayo Clinic also lists amoxicillin as a safe antibiotic for use in pregnancy. However, pregnant women should consult their doctor before taking the medication. The U.S. Food and Drug Administration classifies enhancer as a Class B drug, which means there is no evidence that it is harmful.

Side Effects

The most common side effects of enhancers are nausea, stomach upset, bloating, and diarrhea. Geddes says this is mainly because clavulanic acid can irritate the intestines. Additionally, like other antibiotics, enhancers kill a large group of bacteria, so it may also kill the "good" bacteria in your gut that help digest food. Aujin can also make people more susceptible to yeast infections because it clears out populations of good bacteria that normally inhibit yeast growth. "KDSPE" "KDSPs" "KDSPE" (Image credit: NIH) "KDSPs" People who are allergic to penicillin-type drugs are often also allergic to the auffin protein, which contains amoxicillin. To test for allergy to this drug, doctors can do a skin prick test called a PrePen. In some cases, allergy to Auxin can lead to anaphylaxis, a fatal allergic reaction that can cause narrowing of the airways, swelling of the lips and tongue, and a fatal drop in blood pressure. "KDSPE" "KDSPs" "KDSPE" "KDSPs" "It's in the penicillin family, so allergies are relatively common," said surgeon Dr. Warren Hammert. University of Rochester Medical Center, New York.

Rarely, this drug can cause problems with liver function, causing yellowing of the skin called jaundice.

In rare cases, it can cause colon involvement and lead to serious long-term gastrointestinal problems," Hammett told Live Science.

And some isolated Cases of negative reactions in children to clavulanic acid in enhancers have also been reported.

For example, according to a 2008 study published in the journal Allergology and Immunopathology, 10 children who tested negative for penicillin allergy suddenly became hive-like after taking a booster. History

Humanity obtained their first powerful weapons during germ warfare in the 1920s. Scottish biologist Alexander Fleming was cultivating a bacterium when he noticed that mold growing in his petri dish was killing surrounding bacteria, according to the Nobel Prize website. After extensive research, he discovered that the active agent was what is now known as penicillin (named after the fungus that produces it)

Although penicillin worked wonders, it had some side effects and was active against so many bacteria. has no effect. So in the 1950s, scientists at Beecham Research Laboratories, founded by the same company that made Lucozade soft drink and Brylcreem hair gel, began developing new antibiotics. Their strategy was simple but clever: They used the core chemical structure of penicillin but added different side chains, Geddes said. KDSPE "KDSPs" One of their early successful drugs was amoxicillin, a close relative of penicillin. Amoxicillin and other penicillins share a key molecular structure that helps kill bacteria: a chemical ring called a beta-lactam. "KdSPE" "KDSPs" beta-lactam rings bind to enzymes in bacterial cell membranes. These enzymes are responsible for cross-linking peptidoglycan, the building block of bacterial cell walls. When drugs like amoxicillin disable these membrane enzymes, they prevent the bacteria from producing cell walls even as they continue to destroy their original cell walls. Therefore, "KdSPE" "KDSPs" amoxicillin is considered a breakthrough because it is better absorbed than earlier antibiotics, has fewer side effects of antibiotics such as methicillin, and appears to work against a wide range of bacteria. There's a flaw: At least some drug-resistant strains of bacteria have evolved resistance to amoxicillin and other antibiotics by making an enzyme called a beta-lactamase, which essentially makes the beta-lactam ring Open and inactivate it. But in 1972, Beecham Research Laboratories discovered a drug called Streptomyces, according to a 2007 article published in the International Journal of Microbial Agents. clavuligereus produces a chemical similar to penicillin called clavulianic acid as a byproduct of its fermentation. Like other antibiotics, it has a beta-lactam ring, but it doesn't kill bacteria very well on its own. "KDSPE" "KDSPs" However, when combined with amoxicillin, it creates an excellent antibiotic. Clavulanic acid is the ultimate bait: When bacteria release the antibiotic-snipping enzyme beta-lactamase, it binds to clavulanic acid. Once bound, clavulanic acid changes its shape and permanently inactivates the beta-lactamase enzyme. Clavulanic acid is very effective against several deadly bacteria, including Escherichia coli, Klebsiella aerogenes, Pseudomonas aeruginosa and Staphylococcus aureus, according to a 1977 article in the Journal of the American Society for Microbiology In an article,

"This is truly the first broad-spectrum oral antibiotic with apparently no side effects," Geddes said. At one stage, Augmentin was the world's largest oral antibacterial drug, and "KDSPE" added Resources "KDSPE" National Library of Medicine: Auffin in Michigan State University Antimicrobial Resistance Learning Site: Beta-Lactam Antibiotic Drugs: Amoxicillin/Clavulanic Acid Pregnancy and Breastfeeding Warnings National Library of Medicine: Enhance