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Which is more nucleophilic, triphenylphosphine or tricyclohexylphosphine

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2022-12-05 More than 293 users have adopted his answer

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Triphenylphosphine has high nucleophilicity. Although tricyclohexylphosphine is more basic than triphenylphosphine, the steric hindrance is large. In the SN2 reaction, tributylphosphine has high nucleophilicity. Triphenylphosphine is highly toxic because it easily combines with the hydroxyl group on the active center of cholinesterase.

Answered on 2022-12-05

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Which one has greater nucleophilicity in the SN2 reaction between tributylphosphine and triphenylphosphine? What is the toxicity comparison?

Tributylphosphine has great nucleophilicity. Although triphenylphosphine is more basic than tributylphosphine, it has large steric hindrance. Taking into account the nucleophilicity of tributylphosphine in the SN2 reaction, Big sex. Tributylphosphine is highly toxic, probably because it is easier to combine with the hydroxyl group on the active center of cholinesterase

Anonymous user

Answered on 2011-09-16

2 likes 1672 views

Which one is more polar, triphenylphosphine or triphenylphosphine oxide

Triphenylphosphine oxide is more polar than triphenylphosphine oxide . Because there is a highly polar phosphorus-oxygen bond in the triphenylphosphine oxide molecule, which increases the polarity of the molecule.

Liu's Terminator

Answered on 2017-03-31

1484 views

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