1. Natural environment: Gansu Province is located in the northwest inland, and the natural environment is relatively bad, especially in Qilian Mountain area, where natural disasters occur frequently and have an important impact on the economy.

2. Industrial structure: Gansu Province is dominated by traditional heavy industry, with a single industrial structure and a slow pace of transformation and upgrading.

3. Geographical location: Gansu Province is remote, with inconvenient transportation and relatively little economic exchanges and cooperation with the outside world.