7-up lemonade. "Lemon" is a picture printed on the packaging of 7-up products, and "7-up" is a well-known lemonade brand under Pepsi. 7-Up (formerly known as 7-up in English) has been producing bottled products since 1987. Outside the United States, 7-up is a registered trademark of PepsiCo. It was produced in St. Louis, Missouri in 1929. It originally contained lithium citrate, a sedative. Many early drinks contained pharmaceutical ingredients, which were removed from the formula in 195.