(1) Some drugs can increase the content of prolactin in human plasma, thus inhibiting the secretion of gonadotropin, directly affecting the responsiveness of the central nervous system to sex, causing decreased libido, erectile dysfunction, delayed ejaculation or no ejaculation. The clinical drugs that cause this disease are phenothiazine, enkephalin, reserpine, cimetidine, ranitidine, sulpiride, haloperidol and so on.
(2) Sexual dysfunction is caused by the decrease of plasma testosterone content, which can cause decreased sexual desire, impotence and affect ejaculation function. The drugs that cause this disease are: digoxin, spironolactone, lithium carbonate, adrenocorticotropic hormone and so on.
(3) Affect sexual function through the central nervous system. For example, haloperidol can increase the content of serotonin in the center and reduce sexual function. Long-term use of hypnotics, sedatives, barbiturates, chlorine nitrogen, diazepam, etc. Can lead to impotence.
(4) Sexual dysfunction is caused by affecting peripheral blood vessels and nerve function. For example, guanethidine inhibits ejaculation and reduces sexual desire; Propranolol and metoprolol can cause erectile dysfunction; Bromoprolamine leads to impotence; Sedatives such as codeine, pethidine and methadone may cause sexual dysfunction, such as impotence.