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Will my pet dog pounce on me and rub me? Will I have rabies?

No

It is mainly caused by the rabies virus being transmitted from animals to humans. Rabies virus contains 5 proteins, namely glycoprotein (G), nucleoprotein (N), polymerase (L), phosphoprotein (NS) and matrix (M). The glycoprotein of rabies virus can bind to acetylcholine, which determines the neurophagy of rabies virus. The main source of infection is sick dogs, followed by sick cats and sick wolves. After a person is bitten by a sick animal, the virus in the animal's saliva enters the human body through the wound and causes disease. A small number of patients may also become sick due to contamination of the conjunctiva by the saliva of the sick animal.

Humans are generally susceptible to rabies, and hunters, veterinarians, and animal keepers are more susceptible. After entering the human body, the rabies virus first infects muscle cells, multiplies in small amounts in muscle cells near the wound, and then invades nearby peripheral nerves. The virus then spreads centripetally along the axons of peripheral nerves to the central nervous system without spreading through the blood, mainly invading neurons in the brainstem and cerebellum. The virus replicates in large quantities in the gray matter and travels down the nerves to the salivary glands, cornea, nasal mucosa, lungs, skin and other parts of the body. The main damage caused by rabies virus to the host comes from endosomes, which are eosinophilic particles formed by the accumulation of its discarded protein coat in cells. Endosomes are widely distributed in the central nervous cells of patients and are also the laboratory diagnosis of this disease. an indicator of.

Not all people become ill after being infected. About 15 to 20% of people who are bitten by sick dogs without vaccination will develop the disease. About 50 to 60% of those who are bitten by sick wolves will develop the disease. The factors of the disease are related to the location of the bite. , the degree of trauma, wound treatment, thickness of clothing and whether vaccinations are injected.