In the middle of the Ming Dynasty, Zhu Yuanzhang’s eighth grandson Zhu Houcong (Jiajing) became emperor and widely collected elixirs of immortality. Alchemists Shao Zhijie and Tao Zhongwen obtained many of them from the "Seven Lots of Yunji" compiled by Zhang Junfang in the Song Dynasty. Among the nourishing medicines, the strong points were used to make up for the weak points, additions and deletions were made, and the "furnace and cauldron refining" technology was used to create an "elixir" that was said to be able to live forever. It was named "Guilingji" - taking the immortality of the spirit turtle. . After Jiajing took it, she was indeed in good health and gave birth to children one after another. Shao and Tao were rewarded for this, and Guilingji became the "imperial holy medicine". Tao Zhongwen had an adopted son who was originally from Taigu, Shanxi Province. Under the guidance of Shao and Tao, he refined Guilingji for the emperor and served as the emperor's medical manager. After the deaths of Shao and Tao, he retired and returned to his hometown. He brought back the Guilingji prescription, refined it at home, and gave it to his relatives and friends. Later, Guilingji's prescriptions were introduced to "Guangsheng Pharmacy". From then on, Guilingji became a unique prescription in Taigu, Shanxi, and spread as a commodity. Over the past few hundred years, Guangshenghao has evolved into a series of exclusive Guilingji medicine brands such as Guangshengju, Guangshengyu, Guangkaiyuan and Guangyuyuan, and branches have been set up in major cities in China, Hong Kong and Macao. , so Guilingji, with the word "yuan" as its trademark, became more famous at home and abroad.