The content of testosterone in serum and semen of patients with oligozoospermia and azoospermia is lower than that of normal people. 1987 Facchinetti et al. determined dehydroepiandrosterone and testosterone in semen of infertile patients, and found that the testosterone concentration in semen of oligozoospermia patients was significantly lower than that of normal people. Testosterone concentration in the group with decreased sperm motility also decreased significantly. Androgen is a general term for testosterone, androstenedione, dehydroepiandrosterone and other hormones. Therefore, the decrease of testosterone level is a manifestation of abnormal androgen level. It is reported that 10% of infertile men have abnormal reproductive endocrine axis function. Clinical manifestations are varied, such as decreased libido, pubic hair and armpit hair loss, testicular atrophy, erectile dysfunction and so on. Some people will also show hypothyroidism, such as apathy, listlessness, slowness, lethargy, loss of appetite and so on. Due to pressure, improper lifestyle, unreasonable diet and other reasons, more and more men have abnormal reproductive endocrine axis. This will cause many diseases, such as infertility, sexual dysfunction, insomnia, listlessness and so on. However, many people don't realize that these problems may be related to abnormal androgen levels in the body. Jack believes that low-dose oral androgen supplements are also one of the treatments for infertile patients with decreased testosterone levels. At present, unexplained male infertility is the most common, accounting for about 70% to 80% of the total. There may be genetic reasons, as well as infection, varicocele, environmental pollution, living habits and so on.