The production and excretion of uric acid in the body are similar every day. In terms of production, one third is produced by food metabolism, two thirds is synthesized by the body itself, one third is excreted by the intestine, and two thirds is excreted by the kidney.
Extended data 1. The metabolism of purines in the body is disordered, which leads to the increase of uric acid synthesis or the decrease of uric acid excretion. This is related to the increase of phosphosugar pyrophosphate synthase activity, hypoxanthine-guanine phosphosugar invertase deficiency, glucose 6- phosphatase deficiency, decreased glomerular filtration rate, decreased renal tubular secretion or renal tubular reabsorption.
2. Unreasonable diet structure leads to hyperuricemia. For example, eating acidic food, seafood and high purine food. Besides, it is absolutely forbidden to add seafood to beer. If you eat these three foods for a long time, it will easily lead to the increase of uric acid, which may lead to hyperuricemia and gout. In addition, alcohol can easily accumulate lactic acid in the body, inhibit uric acid excretion and easily induce gout. Patients with hyperuricemia should not drink alcohol, especially beer.
Phoenix net-eating seafood for a long time is easy to cause high uric acid, and drinking soda water can reduce uric acid.