Methanol is inflammable and explosive dangerous goods. If you want to deal in methanol products, you need to apply for a dangerous chemicals business license. If you sell without a license, it is suspected of illegal sales. If the circumstances are serious, he shall be sentenced to fixed-term imprisonment of not more than five years or criminal detention, and shall also or solely be fined not less than one time but not more than five times the illegal income; If the circumstances are especially serious, he shall be sentenced to fixed-term imprisonment of not less than five years, and shall also be fined not less than one time but not more than five times his illegal income or his property shall be confiscated. Whoever commits one of the following illegal business operations and disrupts the market order, if the circumstances are serious, shall be sentenced to fixed-term imprisonment of not more than five years or criminal detention, and shall also, or shall only, be fined not less than one time but not more than five times the illegal income; If the circumstances are especially serious, he shall be sentenced to fixed-term imprisonment of not less than five years, and shall also be fined not less than one time but not more than five times his illegal income or his property shall be confiscated: (1) dealing in franchise, monopoly goods or other commodities whose business is restricted by laws and administrative regulations without permission;

(2) buying and selling import and export licenses, import and export certificates of origin and other business licenses or approval documents stipulated by laws and administrative regulations;

(three) without the approval of the relevant competent departments of the state, illegally engaged in securities, futures, insurance business, or illegally engaged in fund payment and settlement business;

(four) other illegal business activities that seriously disrupt the market order.

Engaged in the operation of second-class medical devices, the operating enterprise shall file with the municipal food and drug supervision and administration department located in the district, and fill in the filing form for the operation of second-class medical devices. The food and drug supervision and administration department shall check the integrity of the information submitted by the enterprise on the spot, put it on record if it meets the requirements, and issue a record certificate for the operation of Class II medical devices.

Legal basis: Article 10 of the Regulations on the Supervision and Administration of Medical Devices.

For the filing of Class I medical device products, the filing person shall submit the filing materials to the food and drug supervision and administration department of the municipal people's government where the district is located. Among them, the product inspection report can be the self-inspection report of the filing person; Clinical evaluation data does not include clinical trial reports, but it can be data obtained through literature and clinical use of similar products to prove the safety and effectiveness of medical devices.