Analysis of whether the human bone marrow with type A blood is suitable for people with type O blood-it has nothing to do with blood type, but depends on HLA typing. Moreover, the blood type will be changed to the donor's blood type after transplantation, because the blood received later is made by the donor's hematopoietic stem cells, and the hematopoietic stem cells were killed before transplantation, so the blood of the original blood type cannot be made. At present, the authoritative hospital for stem cell transplantation in China is the Department of Pediatrics of Beijing Navy General Hospital, the research center for children's intensive care, or the Red Cross? Blue ribbon fund? The only designated hospital with designated funding. The first successful stem cell transplantation in the world was completed in this medical institution, followed by the United States, and China put this scientific research technology at the forefront of the world. Therefore, transplantation therapy has a higher cost performance. All cells are cultured in the department laboratory, and there is no commercial behavior.
Analysis of whether human bone marrow with type A blood is suitable for people with type O blood. 2. Both bone marrow transplantation and hematopoietic stem cell transplantation (from peripheral blood) aim at transplanting hematopoietic stem cells. Because hematopoietic stem cells mainly exist in bone marrow, the early extraction of hematopoietic stem cells can only be achieved through bone marrow puncture, and bone marrow is extracted with a needle for transplantation, which is what you call bone marrow transplantation. The disadvantages of doing so are obvious. First of all, it causes pain to those in bone marrow donor. Imagine how painful it is to stick a needle into your spine. Recovery is slow and risky. Because hematopoietic stem cells also exist in a small amount in autologous peripheral blood, alternative (autologous peripheral blood) hematopoietic stem cell transplantation was born later. In this method, the blood of stem cell donors is taken out of the body, circulated in vitro through special equipment, and finally returned to the body. Related equipment will separate hematopoietic stem cells from the blood; Its advantages are avoiding bone marrow puncture, no pain, quick recovery and low risk;
Brief introduction of bone marrow transplantation and hematopoietic stem cell transplantation;
(1) Autologous Bone Marrow Transplantation (ABMT) or Autologous Peripheral Blood Hematopoietic Stem Cell Transplantation (APBCT): The main purpose of ABMT and APBSCT in the treatment of CML is to prolong the chronic phase or make the advanced patients return to the chronic phase, thus prolonging the survival time of patients.
(2) Allogeneic bone marrow transplantation: This BMT is the earliest attempt to treat CML.
(3) Allogeneic bone marrow transplantation: Allogeneic BMT is almost the only way to completely cure CML at present, and it is also the best treatment for CML.
(4) Treatment of accelerated phase and acute phase Once CML enters the accelerated phase, its condition is unstable, and about 2/3 patients will have acute phase. This stage is the late stage of CML, which is difficult to treat.
Precautions for bone marrow transplantation 1. Keep your skin clean, use 1:2000 chlorhexidine every day in the laminar flow clean room, and use warm water to rub the bath outdoors.
Note 2. Wear clean and soft underwear to avoid scratching the skin, and pay attention to the color, time and area of the rash. Don't scratch when your skin itches, keep the sheets clean and change your underwear frequently.
Note 3. Use chloramphenicol and rifampicin eye drops alternately on time, and use artificial tears when eyes are dry. When keratitis breaks out, patients are required to stay in bed, reading books, watching TV and playing computer are forbidden, and blindfolds are used to cover their photophobia and tears and dim the light.
Note 4. Observe the characteristics of stool, the frequency of diarrhea and the nature of abdominal pain; Accurately record the number, quantity and color of diarrhea; Wash the perianal region with iodophor water after each defecation to keep the perianal region clean.