There is the most accurate average in the database of insurance companies. The average life expectancy of a city or region is the most critical part of the big data of insurance companies, because it is directly linked to profits. Of course, what we want is not the average. After all, everyone wants to live to be 11 years old. So theoretically, is this goal low or high? How long can human beings live?

There are several ways to estimate the approximate life span of a species, mainly the average life span can be estimated by the growth cycle or the number of cell divisions, and this value can still be referenced. Let's take a look at it: biological law estimation

According to the growth cycle of mammals, the life span of ordinary mammals is about 5-7 times that of human beings, and the growth cycle is about 18-19 years, so the maximum life span can reach about 13 years, and the minimum life span can be reached.

According to the growth cycle and division times of human cells, under normal circumstances, the cell division cycle of human beings is about 2-2.5 years, while according to the statistics of scientists, the cell division cycle is about 5 times, so the upper limit is 15 years old and the lower limit is about 1 years old. Of course, this range is also very wide, almost half a century apart! Gompertz model estimation

This model is Benjamin? Gomperts first proposed that he was a self-taught mathematician and actuary in Britain. The Gompertz model was published in 1825 by him, "Functional Expression of Human Mortality and a New Model for Determining Life Danger". Of course, the paper is too complicated. The simple description is that after the age of 3, the mortality rate of human beings will double every eight years! According to this curve, we can calculate that the theoretical limit life of human beings is about 13 years old, but no one can live to this age, because the probability is too small, so push it back, about 122-124 years old!

Gompertz model should be the most accurate of the three conjectures, and Yana is the oldest person in Guinness World Records. Carmante, born on February 21st, 1875, was a French Aral. Her father was 94 years old and her mother lived to be 86 years old. She died in a nursing home on August 4th, 1997 at the age of 122 years and 164 days.

Gompertz model is not only very accurate in calculating the population life model, but also this? S curve? Our time series mathematical model has also been applied to a variety of time-dependent models, including tumor growth, population growth and financial market evolution, with appalling accuracy! What factors determine human life span?

from the above, we know that human cells divide about 5 times, and it is telomeres and telomerase at both ends of chromosomes that determine this division number, and the combination of them completes the division number of cells.

telomere: a small DNA- protein complex existing at the end of the linear chromosome in eukaryotic cells, which together with telomere binding protein constitutes a special? Hat? Structure, the role is to maintain the integrity of chromosomes and control the cell division cycle.

Telomerase: It is a special ribonucleoprotein polymerase with reverse transcription activity in human body. It can synthesize telomere DNA in cells, maintain the length of telomeres, and increase the number of cell divisions, thus enabling cells to proliferate indefinitely.

It sounds as if the life span of human beings can reach infinity, but in fact it can't be desired. Because the activity of telomerase in normal cells of human body is very low, the fuel provided by telomerase to telomeres is very limited. Every time the telomeres of each chromosome are divided, the telomeres will become shorter, so everyone understands the rest. Telomeres need telomerase fuel, but the fuel supply is limited. Finally, when the telomeres reach the critical length, they can't divide any more. Therefore, the life span of the last batch of divided cells in human body expires, and so does the life span. Is there any way to prolong human life?

according to the above description of the number of divisions, we just need to activate telomerase, or introduce telomerase directly into cells in a more violent way? Scientists really did it: Telomerase activator TA-65 (Astragalus compounds) was used to prolong the telomere length. Although the cell experiment was effective, no obvious effect was found in human body. It seems that scientists still need to work hard.

About Hella cells

You should be familiar with Hella cells, which originated from an American black woman, Harriet? Lax's cell line of cervical cancer cells, thinking that after the surgeon took out a sample from her tumor and cultured it, is still proliferating! Different from normal human cells, Hella cell plants will not age, and they can proliferate indefinitely.

Maybe the secret of our human longevity is hidden in Hella cells, but this uncontrolled proliferation may also become a nightmare, and it is impossible to grow a monster. Therefore, it is not so easy to live a long and controllable life. In addition, there are some physical ways to prolong people's life, such as freezing technology and hibernation, which are breaking through research, but this way seems to be contrary to our high standard and strict life, so scientists have to continue to work hard. After all, everyone wants to live longer.