Deputy leader of the overall expert group of the Research and Development Planning Project (863) Stem Cell and Tissue Engineering.
Graduated from Northeast Agricultural University in 1996 and received a doctorate in science. In 1997, he entered the postdoctoral mobile station of the Institute of Developmental Biology, Chinese Academy of Sciences. In 1999, he obtained the qualification of associate researcher at the Institute of Developmental Biology, Chinese Academy of Sciences. From 1999 to 2002, he worked in France.
Postdoctoral fellow in the Department of Molecular Developmental Biology of the National Agricultural Research Center, serving as project leader; selected into the "Hundred Talents Program" of the Chinese Academy of Sciences in 2001.
Assistant to the Director of the Institute of Zoology, Chinese Academy of Sciences, Deputy Director of the State Key Laboratory of Reproductive Biology, and Director of the Stem Cell and Regenerative Medicine Research Center.
Lifetime honorary member of the International GMO Association; Chinese representative of the International Stem Cell Organization (ISCF).
Mainly engaged in research on the mechanisms of differentiation and dedifferentiation, the plasticity and totipotency of stem cells, the plasticity of somatic cells, and somatic cell reprogramming; committed to carrying out basic research/applied basic research related to cloning and therapeutic cloning, and promoting
Transformation of basic research into clinical applications.
A variety of cloned animal models (rabbits, mice, cattle, goats, rats, ferrets) have been established; mouse therapeutic cloned embryonic stem cell banks, human embryonic stem cell lines, and parthenogenetic stem cell lines have been established; improved inventions
He has developed 4 somatic cell nuclear transfer technologies and obtained one cloning technology invention patent.
In 2002, it was the first time in the world to use cloned somatic cells to clone rats. The research content was published in "Science".
In July 2009, an article was published in "Nature". For the first time, iPS cells were used to obtain viable and reproductive mice through tetraploid blastocyst injection, thus proving the totipotency of iPS cells for the first time in the world; April 2010
An article published in the Journal of Biological Chemistry last month discovered and clearly demonstrated for the first time the key genetic determinants that determine the pluripotency of mouse stem cells, and can be used as a molecular marker to judge the pluripotency level of stem cells.
He has successively won the "China Youth May 4th Medal", the China Youth Science and Technology Award, the International Transgenic Research genOway Award, the Ho Leung Holey Foundation Science and Technology Award, the France-China Science and Technology Promotion Association Biotechnology Award (AFCRST), and the French Young Chinese Entrepreneurs Association Annual Scientific Research Award.
, the Bayer Young Scientist Award of the Chinese Academy of Sciences (CAS-Bayer), the Outstanding Youth of the Chinese Academy of Sciences, and many other awards; its research results - verifying the totipotency of iPS cells - were selected as one of the top ten medical breakthroughs of the year selected by Time Magazine in the United States in 2009.
, was elected as one of the top ten science and technology progress news in China in 2009 and one of the top ten news in basic research in China in 2009 selected by academicians of the two academies.
On December 7, 2015, he was elected as an academician of the Chinese Academy of Sciences.