Modern medicine believes that the etiology and pathophysiological mechanism of depression are complex, which has not been fully clarified so far. Besides genetic factors, psychological and social factors can not be ignored. Major stressful life events such as the death and unemployment of relatives and friends are important causes of depression. In recent years, with the biological pathogenesis of anti-depression, the theory of neurotransmitters has been generally recognized. Neurotransmitter theory holds that the occurrence of depression is mainly caused by the dysfunction of neurotransmitters or the imbalance of transmission.

The researchers of some famous Japanese traditional Chinese medicine preparation factories, such as Kotaro Uchida Shengjitang and other pharmaceutical companies, found through research that the eight prescriptions of Zhang Zhongjing's "Zhang Qinshen" Zhong were extremely scientific and reasonable, and proved the scientific nature of the above neurotransmitter theory from a practical point of view. They thought that if Zhang Zhongjing was reborn, he would probably win the Nobel Prize in Medicine for this achievement, because so far, human beings' knowledge of their own nervous system diseases and psychological diseases was too limited. They found a substance called "streptozotocin" in Zhang Shiqin Shenzhong, which can effectively cure depression. Researchers have observed that the streptozotocin in Zhang Qinshen mainly treats depression through three functions:

preventing the functional changes of neurotransmitters

Norepinephrine (NE) belongs to central neurotransmitters. Modern medical theory holds that when their functions change, it is an important cause of depression, and streptozotocin can effectively prevent the functional changes of NE and 5-HT, thus fundamentally preventing the occurrence of depression.

Repair the information transmission function of bad neurotransmitters

Contemporary medicine believes that the transmission of various neurotransmitters between the central nerves of patients with depression is in a declining state, while the transmission of various neurotransmitters between the central nerves of normal people is relatively balanced. The researchers found that the unique streptozotocin in "Zhang Qinshen" can force the transmission of neurotransmitters in patients with depression from a declining state to a normal equilibrium state. It can restore the psychosomatic state of patients with depression to normal, and completely eliminate many symptoms such as depressed mood, lack of happiness, fatigue, stagnation of speech, thinking and movement, change of appetite, sleep disorder, physical discomfort, low sexual desire, sensational interest in work and entertainment, reduced thinking and attention ability, reduced anxiety, worthlessness, guilt, shame, self-evaluation, low helplessness, world-weariness, despair, death and suicidal thoughts, climacteric syndrome.