If a Madrid trademark application designates China, how is the three-year non-use period calculated for its cancellation? Which time should be used as the starting time? Trademark Office or International Bureau? Article 49 of the Implementation Regulations of the Trademark Law stipulates: In accordance with the provisions of Article 49, paragraph 2, of the Trademark Law, an application for cancellation of an internationally registered trademark 1. The trademark shall be filed with the trademark 3 years after the expiration of the time limit for rejection of the application for international registration of the trademark. 2. If you are still in the process of rejection review or objection when the rejection period expires, you should file an application with the Trademark Office 3 years from the effective date of the decision to approve registration made by the Trademark Office or the Trademark Review and Adjudication Board. According to this regulation, it is the Trademark Office or the Trademark Review and Adjudication Board rather than the International Bureau.