In 2006. Nais brand toothpaste is specially added with vitamin C, vitamin E and water-soluble mineral salts according to the dental health status of children in China. It was released and put on the market in March 2006. Nais toothpaste not only created a brand-new category of children's toothpaste, but also set off a strong trend of toothpaste in China children's toothpaste market.