and "r" is the abbreviation of English "register", which means "registration" in Chinese. When a commodity or service is marked with this mark, it tells people that the graphics or words it marks are not only trademarks, but also registered trademarks, which are protected by national laws and cannot be used by any other individuals or organizations without authorization. Now you know the difference between TM and R. "TM" is a trademark logo and "R" is a registered trademark logo, and their legal protection is different. When the trademark has not become a registered trademark, mark "TM", which is to tell the public that this graphic or text is used as a "trademark" of goods or services, not a name or advertising, so as to prevent the graphic or text marked by it from flowing into the public domain and not being able to apply for a registered trademark and enjoying exclusive rights; Marking it with "TM" at the same time can also be used as proof of using the graphic or text as a trademark. When applying for registration of a trademark, it enjoys the right of prior use. When a trademark becomes a registered trademark, it can be marked with "R" or "Note" in the upper right corner or lower right corner, or directly marked as "registered trademark". Remember that the registration mark must be placed in the upper right corner or lower right corner of the trademark, which is stipulated in the Regulations for the Implementation of the Trademark Law of the People's Republic of China. Another point to note is that after applying for trademark registration and obtaining the Notice of Acceptance issued by the State Trademark Office, it is still not allowed to mark the registration mark on the trademark before the Trademark Registration Certificate, because the Notice of Acceptance issued by the State Trademark Office is only the beginning of the trademark registration procedure. This Notice of Acceptance only indicates that the Trademark Office has accepted the application for trademark registration, but does not indicate whether the application is approved. In fact, although a considerable number of trademark registration applications have been accepted by the Trademark Office, they have been rejected after examination and finally failed to register successfully. Therefore, it is suggested to mark "TM" instead of "R" during this period, otherwise it will constitute an illegal act of impersonating a registered trademark, and a fine of less than 2% of the illegal business amount or less than 2 times of the illegal profit will be imposed. OTC is the abbreviation of Over The Counter in English, especially for over-the-counter drugs in the pharmaceutical industry. The definition of over-the-counter drugs in China's Ministry of Health is as follows: it is a drug that consumers can buy directly from pharmacies or pharmacies without a doctor's prescription, and it can be used safely without the guidance of medical professionals.