Aspirin is no stranger to everyone, especially friends with cardiovascular and cerebrovascular diseases, who basically take aspirin for a long time or even for life.
Side effects are our biggest headache. Taking aspirin for a long time can cause digestive tract ulcers and even gastrointestinal bleeding.
No matter in the hospital or online, many friends take aspirin after meals, because the reason is simple: there is food in the stomach after meals, and taking aspirin at this time will definitely cause less irritation to the stomach and reduce the side effects of aspirin.
This seemingly simple truth: take aspirin after meals!
Aspirin we take for a long time is generally divided into two dosage forms, one is ordinary aspirin and the other is enteric-coated aspirin.
Aspirin is different, taking time is different!
1897, felix hoffman, a German, synthesized acetylsalicylic acid with the support of Bayer. Its purpose is to treat rheumatoid arthritis for father, and the effect is excellent. Later, aspirin was widely used to relieve fever and pain.
The research and development of aspirin has to be mentioned by Artur Eichengreen, a Jewish chemist. It was eichengreen who led felix hoffman to invent aspirin.
During World War II, Nazi rulers refused to admit that the inventor of aspirin was a Jew, so they put the title of aspirin invention on Hoffman alone and put Artur eichengreen in a concentration camp.
After World War II, Artur Eichengreen was released, and Bayer consulted all relevant files, which finally restored the historical features of this invention. It is pointed out that Artur eichengreen played an important role in the invention of aspirin.
So aspirin was invented by Jews Artur eichengreen and Felix Hoffman.
Because Bayer sponsored the invention of aspirin, Bayer obtained the registered trademark of aspirin 1899 on March 6 after successful research and development.
Later, the medical community has been debating whether aspirin is good for the heart.
Until 197 1 year, scientists found that aspirin can resist the coagulation of platelets in blood, thus maintaining the blood supply to the heart and protecting the heart. However, the clinical research on aspirin to prevent heart disease is too few and unconvincing.
1983 2207 1 American healthy male doctors participated in a large-scale clinical study, which originally lasted for eight years and was terminated prematurely in the fifth year. The reason is that aspirin is so effective
The mid-term results of the study prove that aspirin can reduce the risk of myocardial infarction by 44%, the incidence of the first fatal myocardial infarction by 66%, and the incidence of the first myocardial infarction in diabetic patients by 665,438+0%.
For ordinary aspirin, taking it after meals has the least irritation to the gastrointestinal tract, because aspirin can stimulate the stomach and intestines, and taking it after meals can reduce irritation. This is a particularly simple fact that we started talking about.
Bayer coated 1993 aspirin enteric-coated tablets because people discovered the side effects of aspirin. This tablet is not easy to dissolve in the stomach until it acts in the intestine, thus reducing the side effects of stomach discomfort. So aspirin, or enteric aspirin, was born.
Aspirin is rapidly degraded into salicylic acid after absorption. The peak time of aspirin and salicylic acid in blood is 10-20 minutes and 0.3-2 hours respectively.
Aspirin enteric-coated tablets are acid-resistant, so they are insoluble in acidic gastric juice and soluble in alkaline intestinal juice. The absorption of aspirin enteric-coated tablets is 3-6 hours later than that of ordinary tablets.
If it is aspirin enteric-coated tablets, it is best to take it half an hour before meals. Aspirin enteric-coated tablets have the characteristics of acid resistance but alkali resistance.
Taking aspirin enteric-coated tablets before meals, because it is in a strong acidic environment on an empty stomach, after taking aspirin enteric-coated tablets on an empty stomach, the gastric emptying is fast and the retention time is short, which can reduce the damage to gastric mucosa and directly enter the intestinal tract for dissolution. Therefore, it can be said responsibly that it is better to take enteric aspirin on an empty stomach before meals, which can reduce the side effects of aspirin.