Molecular genetics of cardiovascular disease

Research work:

Focusing on the pathogenesis of hypertension as the main research direction, through population genetics and molecular biology technology, for the first time in the world, the arachidonic acid ω-hydroxylase gene CYP4F2 was identified as a susceptibility gene to hypertension. The enhancement of its expression and activity leads to an increase in the metabolite 20-HETE, which is related to the occurrence of hypertension in the Chinese population. Related.

Project (first person in charge):

1. National Natural Science Foundation of China

"NF-κB signaling pathway regulates P450-ω hydroxyl in high salt "Role in enzyme expression" (30800463) 2009.01~2011.12

Awards:

1. Second Prize of the 2010 Academic Achievement Award for Higher Education Institutions of the Ministry of Education (Second Completer)

2. The first prize of the 2008 Liaoning Provincial Natural Science Academic Achievements Award (the first completer)

3. The first prize of the 2008 Liaoning Provincial Science and Technology Progress Award (the third completer) person)

4. 2008 Shenyang Science and Technology Progress Award Second Prize (third person)

Graduate student training:

To train one master’s student.

Teaching work:

Assume the teaching tasks of "Medical Genetics" for undergraduate students and "Human Development and Genetics" for the seven-year program.