According to the relevant regulations of the project application of the National Natural Science Foundation of China, all research involving human experiments needs to be completed before the application. The following explanation is made for this ethical review: 1, and this ethical review of human biomedical research is conducted online. After logging into the system, improve the attached personnel information, academic experience in talent service and the scanned copy of my handwritten signature. Select "Application of Medical Scientific Research Ethics" in "Teaching and Scientific Research Management" and complete the required contents as required. After submitting the application, you can download and view the generated approval form. If there is any omission, please withdraw the modification and resubmit.