According to research, he was born in the first year of Yongjia in the Han Dynasty (145 AD) and died in the 13th year of Jian'an (208 AD). This research is very doubtful. Because the "Book of the Later Han Dynasty·Hua Tuo Biography" records that Hua Tuo was "a hundred years old, but still had a strong appearance, and people at the time thought he was an immortal"

It is also said that he lived to be 150 or 60 years old He still maintains the appearance of being over sixty years old, and is recorded as having a childlike appearance. According to this, Hua Tuo may have lived more than sixty-four years. Hua Tuo lived in the late Eastern Han Dynasty and the early Three Kingdoms period. At that time, the warlords were in chaos, floods and droughts occurred, epidemics were prevalent, and the people were in dire straits. Wang Can, a famous poet at that time, wrote the following two sentences in his "Seven Sorrow Poems": "You can't see anything when you go out, the plain is covered with white bones." This is a true portrayal of the social situation at that time. Witnessing this situation, Hua Tuo hated the feudal tyrants who committed many evil deeds and sympathized with the oppressed and exploited working people. For this reason, he did not want to be an official. He would rather hold the golden hoop and run around to relieve the people's suffering.

At the end of the Eastern Han Dynasty, three outstanding medical scientists were born in our country, known as the "Three Miracle Doctors of Jian'an" in history. Among them, Dong Feng lived in seclusion in Mount Lu and left behind a well-known story about the apricot forest; Zhang Zhongjing wrote "Treatise on Febrile and Miscellaneous Diseases" with rigorous theories and methods, and was hailed as the "Sage of Medicine" by later generations; while Hua Tuo went deep into the folk and traveled all over the Central Plains and Jianghuai River. Pingyuan has created many medical miracles in the clinical diagnosis and treatment of internal medicine, surgery, gynecology, and pediatrics. It is especially famous for its Chuangma Fei San (clinical anesthetic) and laparotomy. Later generations praised doctors as "Hua Tuo's reincarnation" and "Yuanhua's rebirth", which shows his far-reaching influence. Hua Tuo was an outstanding medical scientist in the Eastern Han Dynasty. Both "Book of the Later Han" and "Three Kingdoms" are dedicated biographies of him. The Hua family was originally a prominent family, and one of its descendants settled in Xiaohuazhuang (now Huatuo Town, Qiaocheng District), a beautiful village more than ten miles north of Qiao County. By the time Hua Tuo arrived, the family had declined, but the family placed great expectations on Hua Tuo. Judging from its name and characters, the name "Tuo" means load, and "Yuanhua" means education. Hua Tuo studied hard since childhood and recited ancient books such as "Book of Songs", "Book of Songs", "Book of Changes", "Book of Rites", "Spring and Autumn Annals", etc., and gradually developed a high level of cultural literacy.

Hua Tuo practiced medicine without a master. He mainly studied the medical classics of previous generations and continued to study and make progress in practice. At that time, my country's medicine had achieved certain achievements. Medical classics such as "The Yellow Emperor's Internal Classic", "The Eighty-one Difficulties of the Yellow Emperor", and "Shen Nong's Materia Medica" were published one after another. Principles and guidance, acupuncture, drugs and other diagnostic and treatment methods have been basically established and widely used. However, ancient doctors, such as Bian Que during the Warring States Period, Cang Gong in the Western Han Dynasty, Fu Weng and Cheng Gao in the Eastern Han Dynasty, left behind the legacy of not seeking glory and profit. Wealth, wealth, and touching stories of helping the world with medicine all his life, all of which not only provided the possibility for Hua Tuo to study medicine intensively, but also cultivated his sentiments.

Hua Tuo is good at the research of medicine. "Book of the Later Han Dynasty·Hua Tuo Biography" says that he was "commonly versed in several classics and knew the art of nourishing one's nature", and was especially "proficient in prescriptions and medicines". People called him "the miracle doctor". He once compiled his rich medical experience into a medical work called "Qing Sang Jing", but unfortunately it has not been handed down. But it cannot be said that his medical experience was completely lost as a result. Because many of his accomplished students, such as Fan A who is famous for acupuncture, Wu Pu who wrote "Wu Pu's Materia Medica", and Li Dangzhi who wrote "Materia Medica", partly inherited his experience. As for the existing "Zhongzang Jing" by Hua Tuo, it was written by a Song Dynasty person and published under his name. But it may also include some of the contents of Hua Tuo's writings that were still remaining at that time.