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"Being a stranger in a foreign land makes me miss my family more often during the festive season". Many wanderers who study hard in other places or live in a foreign land will take advantage of the Mid-Autumn Festival to reunite with their families and enjoy family happiness. At this time, there are many gifts to accompany them home. Moon cakes and grapefruit gift boxes that are suitable for the occasion must be the best choice. Among them, grapefruit hides the dangers and taboos of interaction with drugs, which need special attention from the public.

Pomelo is highly loved by Chinese people.

Pomelo belongs to Citrus of Rutaceae, alias Wendan, and it has a wide variety, including scraped Madou Wendan Pomelo, Madou White Pomelo, White Pomelo, Stone Pomelo, etc. Among them, Madou Wendan Pomelo is the most widely known. Because grapefruit is rich in vitamin C, according to the Taiwan Province Food Composition Database, every 1g of grapefruit contains about 5mg of vitamin C, which has reached half of the recommended amount of dietary nutrients for Chinese people (the recommended amount of vitamin C for adults is 1mg per day), which has a positive effect on the prevention of colds and the improvement of immunity. Except grapefruit pulp, grapefruit-related peripheral products are deeply loved by the public, such as citron tea, grapefruit peel, grapefruit sauce and so on.

sour and sweet grapefruit is rich in vitamins C, B1, B2, protein, dietary fiber, calcium, phosphorus, iron and other minerals, with diverse nutritional components, and has good auxiliary effects on the body, such as moistening the lungs and throat, invigorating the stomach and regulating the intestines. However, for people who take some specific drugs, it is necessary to try to avoid taking grapefruit. Have you heard the warning that "you can't take medicine with grapefruit juice"? Because grapefruit contains ingredients similar to grapefruit, it is easy to interact with some drugs, which may lead to drug poisoning or drug rejection in patients, and even lead to death in severe cases.

Avoid taking these five "drugs" with grapefruit. Older people should pay more attention.

Because grapefruit contains a component called Furanocoumarin, this component will inhibit the enzyme -CYP3A4 used by human body to metabolize specific drugs. If this enzyme fails to work, the metabolism and decomposition speed of drugs in the body will slow down, which will lead to the drug staying in the body for a long time, leading to blood.

however, not every drug will have a negative impact on the interaction with coumarin, and there are mainly five drugs that need special attention. For example, calcium channel blockers (amlodipine, felodipine), statin (atrovastatin, lovastatin, simvastatin), antiarrhythmic drugs (amiodarone) and immunosuppressants (cyclosporin), some hypnotic sedatives and antidepressants, etc., all belong to drugs that will have interaction, so be careful! The Harm Relief Foundation reminds that the elderly, in particular, need to be more careful, because their metabolic ability is inherently poor, and they have low tolerance for high-concentration drugs, and they are the main users of chronic drugs. They or their families and caregivers must pay attention to avoid the elderly at home taking grapefruit, grapefruit or citrus fruits, so as not to cause side effects of drugs and hurt their health. Classification examples combined with grapefruit or grapefruit Results Atorvastatin(ex: Lipitor? ) Lovastatin(ex: beauty fat? ) Simvastatin(ex: vegetarian? ) Interaction may lead to muscle disease, rhabdomyolysis and even acute renal failure. Antihypertensive drug (calcium channel blocker) Felodioine(ex: propranolol? ) Nifedioine(ex: Guan Dayue? ) Verapamil(ex: Heart Ping Shu? ) Amlodipine(ex:a pulse is excellent? ) may cause adverse reactions such as low blood pressure and rapid heartbeat, and may seriously lead to ischemic myocardial infarction. Diazepam(ex: Fanning? Midazolam(ex: sleep guide? Triazolam(ex: Hao Lexin? ) a possible antiarrhythmic drug amiodarone(ex: metoprolol? ) immunosuppressant cyclosporin(ex: Xin ti mu? Adverse reactions such as nausea, headache, paralysis, cramps, nephrotoxicity, etc. ) the increase of drug blood concentration increases the risk of adverse reactions

Health 99 provided by the Ministry of Health and Welfare of the Executive Yuan and the National Health Service

Care should be taken for drug safety, and a professional pharmacist is needed if you have doubts

Moreover, the time limit for grapefruit to inhibit drug metabolism may last for several hours or even two or three days, even if you take it at intervals, there are still risks, so the best way is to "don't eat" grapefruit. However, it's rare to spend holidays with family members, so it seems a bit unreasonable to not eat at all. Sun Guolun, a pharmacist in the pharmacy department of the Affiliated Hospital of Taipei Medical College, said that the last alternative is to "taste it". Eating one or two tablets is within the acceptable range, and you must never eat more than this range!

If you are not sure whether your medicine will have adverse interaction with grapefruit, grapefruit and other foods, it is recommended to go to the hospital or the community pharmacy clinic near your home to ask a professional doctor or pharmacist. Don't drink or eat grapefruit and then take medicine under uncertain circumstances. The safety of medication needs to be careful. I hope everyone can have a happy and safe Mid-Autumn Festival! Topic: Mid-Autumn Festival, Nutrition Questions, Enzymes, Health Care.