No, Duoyida can be stored for 14 days without refrigeration at a temperature not exceeding 30℃, so it will not lose its activity if it is stored at room temperature for two hours. As a new hypoglycemic agent, Dulaida injection is a weekly preparation of GLP- 1 receptor agonist, which can improve insulin resistance and islet morphology, promote islet cell proliferation, inhibit its apoptosis, inhibit liver glucose output, gastrointestinal peristalsis, and delay gastric emptying, thus playing a hypoglycemic role.